Any Experience with Agmatine or DLPA?

Madmaxnightrider, I take DLPA 500 mg daily; and like you, I find that it potentiates kratom. The supplement I take is a 500 mg capsule, which was recommended by an M.D. From what I've read, the safest, most effective dose of DLPA is not known. But I've also read that no one should take more than 3 grams daily.

Regarding phenibut, I've taken 500 mgs (1/2 gram) daily. The max dose is 500 mgs. 3x/day. At the time, I found it helpful.
I learned of the dosage from a translated Russian medical article. It's been used clinically there for over 50 years.

Depression and generalized anxiety have always challenged me. Then, a few years back, I was diagnosed with
a degenerating neuromuscular condition, for which there is no cure. I don't talk about it much, because I believe thoughts and words carry their own power to manifest outcomes.

However, because of the way my life is changing; and especially due to a major set back, I recently went on Effexor and Ativan, which are helping me do a better job of coping at this time. My plan is to wean off these as soon as I'm in a "better place" mentally & emotionally. I still take kratom for pain & energy. Because of the effexor, I stopped taking phenibut, and I decided against agmatine, because of the possibility of serotonin syndrome, which can be fatal.

I continue to research natural alternatives so I can come up with a plan to implement post effexor and ativan. I need to check out other online forums that deal with these issues. Recently, I found neurotalk.org to be a good one that's moderated by professionals. The forum is high-quality, and very helpful for several medical conditions.

Hope this little bit of info helps. Take good care of yourself. 🙂

Welcome to the Forum Donut. Thanks very much for the Info that you have Provided me with. I am currently taking 500 mg of Agmatine 3 times daily with my Kratom. I have tried DLPA but it makes me feel weird & spaced out so I had to stop taking it. It could be interacting with another medicine that I am taking.

I have been on about at least a Dozen Depression Meds over the past 10 years & Finally found Prozac which works. Prozac keeps me from going back into deep depression & Kratom keeps me feeling like Life is worth living. I have been on Effexor & Ativan at one time. They are both good meds.

I have tried agmatine for the last couple weeks and have noticed good results. I was up to 14g a day after my two months of wisdom teeth extraction pain. Now I'm back to 6-8. I have read it takes a week before it starts really working. I take 750mg in the morning and evening/5pmish for three days then one day off. says on the package 3 days on one day off. I wonder though about the taking it for a week before it starts working well. It is water soluble so I figured it would work threw the body after a couple days and would not have a build up effect.

So Max, what brand of agmatine are you buying? I always worry about whether I'm buying garbage or good with things like that! And Laurie if you can let me know too, that would be great.

Max, maybe try cat's claw. I can't remember if you said you had or not, but if it could replace a night time dose of kratom, it might be helpful. I stopped taking ativan with the help of kratom and cat's claw, and I am soooo happy about that! The weird thing is that I never realized that it was leaving me depressed the next day. I stopped taking it - I made no conscious decision to stop, I just didn't need it and I felt no effects of withdrawal. It's been 3 weeks now. A few nights ago I was really excited (a great chance to buy some vintage Chinese jewelry cam around woohoo!) and I knew I wasn't going to be able to sleep, so I took a .5 dosage of ativan. I was so shocked at how down I felt the next day, really dragging. And the fact that the Chinese jewelry deal was going fine should have meant I would be very happy. So I knew it was the ativan. Anyhow, I found that I had one night of weird dreams with the cat's claw but nothing worse than that. Wishing you the best luck Max, and the same for everyone else on this thread.

Hi Kitsune! Hope all is well with you. I’m using whatever vendor has the cheapest agmatine on Amazon. I’ve tried 2 brands from Amazon and no worries about product quality. However, it needs to be used on an empty stomach also, and it makes me get hungry. So I’m almost always canceling it and kratom out not long after using it. So I’m down to using only one gram in the morning only when I’m going for coffee and walking. No afternoon or evening dose needed. I put on 20 pounds in the last 6 months. No cool 🙁 It’s not all the agmatine. I’ve been craving the wrong foods and BUYING the wrong foods. So that’s under ‘change of management’ in addition to weaning off of unnecessary botanical (or not) substances. Cutting down on kratom, agmatine, Kava, kanna, all of it. Planning to have fewer bags of “stuff” I “need” as the new year approaches. Including ice cream! LOL
However, Joe at Re-Leaf LLC is carrying agmatine as part of his product line. He just recently added it to his portfolio of products. I would recommend you give his product a try for that EXTRA bit of safety and assurance with regard to safety and product purity. If I were planning to continue agmatine, he would be my resource. I’m pretty sure he has a better variety of sizes of bags to choose from compared to Amazon. But it’s not an expensive product ANYWAY, and I’ve had no problems whatsoever with product safety or purity.
DLPA didn’t do anything for me, but some people have sworn it helps them. Thankfully, I’m just not lacking in the area that it helps people I guess.
Let me know if you want more specifics. Nice e-seeing you! Laurie

It was really odd! Cravings for foods I don’t approve of! Humiliating to buy them, and consume them! Mom used to eat it, so it was her fault I had that stuff around (lol), but even she has had ENOUGH. I’ll let you know how we do on our new program. We are a good TEAM!

Hi BoMalley,
I also pack the caps around in my purse and near the bed for bad pain relief when everything has been tried. I buy them capped so am not aware of the taste, but it’s costly. Your plan is much more conducive to my budget.

So Max, what brand of agmatine are you buying? I always worry about whether I'm buying garbage or good with things like that! And Laurie if you can let me know too, that would be great.

Max, maybe try cat's claw. I can't remember if you said you had or not, but if it could replace a night time dose of kratom, it might be helpful. I stopped taking ativan with the help of kratom and cat's claw, and I am soooo happy about that! The weird thing is that I never realized that it was leaving me depressed the next day. I stopped taking it - I made no conscious decision to stop, I just didn't need it and I felt no effects of withdrawal. It's been 3 weeks now. A few nights ago I was really excited (a great chance to buy some vintage Chinese jewelry cam around woohoo!) and I knew I wasn't going to be able to sleep, so I took a .5 dosage of ativan. I was so shocked at how down I felt the next day, really dragging. And the fact that the Chinese jewelry deal was going fine should have meant I would be very happy. So I knew it was the ativan. Anyhow, I found that I had one night of weird dreams with the cat's claw but nothing worse than that. Wishing you the best luck Max, and the same for everyone else on this thread.

I really need to try Cat's Claw. I've heard very good things about it.

This is the Agmatine that I am currently using:
https://www.amazon.com/100g-3-53oz-Agmatine-Sulfate-Powder/dp/B0145LNV1E/ref=sr_1_2?m=A1VHDTT9YRAGY6&s=merchant-items&ie=UTF8&qid=1509700710&sr=1-2&keywords=agmatine

I take about Half a Gram of Agmatine 3 times a day. I needed to gain weight because I am just Muscle, Flesh & Bone & about 5% Fat if that. I have gained about 10 Pounds in the last 2 weeks from Agmatine & I Run 5 Miles a Day.

Thanks you guys!